Download Amobarbital Effects and Lateralized Brain Function: The Wada by David W. Loring, Kimford J. Meador, Gregory P. Lee, Don W. PDF

By David W. Loring, Kimford J. Meador, Gregory P. Lee, Don W. King

The intracarotid amobarbital (or Amytal) strategy is usually known as the Wada try in tribute to Juhn Wada, the general practitioner who devised the process and played the 1st uncomplicated animal examine and scientific experiences with this system. Wada trying out has develop into an essential component of the pre­ operative overview for epilepsy surgical procedure. curiously, although, Wada at the beginning built this system as a strategy to evaluate language dominance in psychiatric sufferers so that electroconvulsant treatment may be utilized unilaterally to the non-dominant hemisphere. Epilepsy surgical procedure has matured as a achievable remedy for intractable seizures and is not any longer confmed to some significant universities and clinical institutes. but, as is more and more transparent through analyzing the surveys of methods utilized by epilepsy surgical procedure facilities (e.g., Rausch, 1987; Snyder, Novelly, & Harris, 1990), there isn't purely nice heterogeneity within the tools used in the course of Wada checking out to evaluate language and reminiscence services, yet there additionally appears to be like a scarcity of consensus concerning the theoretical assumptions, and maybe, even the targets of this procedure.

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Additional info for Amobarbital Effects and Lateralized Brain Function: The Wada Test

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In the remaining patient (Case 3), a memory deficit was reported 4 weeks post-operatively. Since this patient later served as a physician's secretary, she substantially regained the ability to remember daily activities in order to perform her job adequately. Unfortunately, longer follow-up and formal memory description was not obtained on this patient. Scoville & Milner (1957). 's profound post-surgical amnesia firmly established the role of bilateral mesial temporal lobe structures in recent memory.

However, the males also had an earlier age of probable neurologic involvement compared to the females. The most comprehensive studies of right hemisphere language and neuropsychological function have produced discrepant results. Mateer & Dodrill (1983) compared neuropsychological performances of left- (n=75), mixed- (n=6), and right-cerebral (n=9) language dominant patients, and observed no differences on Full Scale IQ, Verbal IQ, Performance IQ, or the Wechsler Memory Scale subtests. More "expressive" errors were reported on the Reitan-Indiana Aphasia Screening Test by the group with bilateral language.

One of 2 left-handed patients was right cerebral language dominant, and the other patient displayed bilateral language, with greater right than left representation. Although the authors acknowledged the difficulty of this technique in the identification of patients with bilateral language, they were encouraged that similar non-invasive testing might eventually be substituted for the Wada language evaluation. In summary, standard dichotic listening as well as visual half-field techniques have not proven to be sufficiently consistent to identify language dominance in individual patients.

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